China Oncology 2013;(9):765-771

doi:10.3969/j.issn.1007-3969.2013.09.012

Advances in breast cancer related nomograms

Ru YAO ; Bo PAN ; Qiang SUN ; Ying XU ; Changjun WANG ; Yidong ZHOU ; Feng MAO ; Yan LIN

Keywords

Breast cancer; Nomogram; Sentinel lymph node; Non-sentinel lymph node; Metastasis; Prediction

Country

China

Language

Chinese

Abstract

Breast cancer is the leading cause of malignancy-related mortality in women worldwide. The more accurate prediction of lymph node metastasis and evaluation of personalized prognosis of breast cancer patients could provide evidence and reference for individualized comprehensive treatment and clinical decision-making. Nomogram is statistical calculation model developed to generate individualized prediction of a certain clinical event through the factors associated with it. Currently breast cancer related nomogram models is most commonly used in the prediction of non-sentinel lymph node status in patients with sentinel lymph node-positive breast cancer, sentinel lymph node metastasis in clinical node-negative breast cancer and prognosis evaluation of breast cancer. This article reviewed the recent advances in breast cancer related nomograms according to the above mentioned three aspects, and evaluated respectively the predictive factors, accuracy, characteristics and clinical application potential.