International Journal of Cerebrovascular Diseases 2013;21(8):638-640

doi:10.3760/cma.j.issn.1673-4165.2013.08.009

Mechanisms of bone mesenchymal stem cell therapy for ischemic stroke

Lian YANG ; Zhaojun WANG ; Gelin XU

Keywords

Stroke; Brain Ischemia; Bone Marrow Transplantation; Stem Cells; Neurogenesis; Neovascularization,Physiologic; Neuronal Plasticity

Country

China

Language

Chinese

Abstract

Studies in recent years have shown that the mesenchymal stem cells promote nerve repair and improve neurological function after ischemic stroke.As a major source of mesenchymal stem cells,bone mesenchymal stem cells have potential and broad prospects in the treatment of ischemic stroke.This article reviews the sources,characteristics of mesenchymal stem cells,and the pathogenesis of mesenchymal stem cell transplantation in the treatment of ischemic stroke and prospects.