Journal of Kunming Medical University 2013;(12):117-118

The Clinical Efficacy of Phentolamine in Treatment of Severe Hand-foot-mouth Disease

Qiong LIU ; Zengqing DU ; Yanchun WANG ; Yongkun HUANG ; Mei LIU

Keywords

Hand- foot- mouth disease; Phentolamine; Clinical efficacy

Country

China

Language

Chinese

Abstract

Objective To observe the clinical curative effect of phentolamine in the treatment of severe hand-foot-mouth disease (HFMD) . Methods We observed the clinical symptoms and related index changes before and after treatment of 62 cases of severe HFMD patients who were treated by the basis of conventional therapy with additional phentolamine. The blood pressure of patients was closely monitored,and the dosage of phentolamine was adjusted. Result The blood pressure and heart rate of sick children who used phentolamine improved significantly, the difference was statistically significant ( <0.05) . Conclusion Phentolamine has significant clinical curative effect in treatment of server HFMD.