Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2009;(18):824-826

doi:10.3969/j.issn.1001-1781.2009.18.003

A study of intratumor microvessel density and lymph node micrometastasesof pN0 supraglottic laryngeal squamous cell carcinoma

Binghua LI ; Yaping XU ; Lizhong SU ; Mingyuan CHEN

Keywords

laryngeal neoplasms; microvessel density; micrometastases

Country

China

Language

Chinese

Abstract

Objective:To investigate the correlation between intratumor microvessel density (IMVD) and lymph node micrometastases. Method: IMVD and lymph node micrometastases were stained with CD105 and CK19 antibody by immunohistochemical method of SABC respectively. Result:IMVD marked with CD105 antibody corre-lated with T stage and lymph node micrometastases(P<0.01). Conclusion: The result show that IMVD marked with CD105 antibody highly correlated with lymph node micrometastases. It could be a index to evaluate the prog-nosis of patients with pN_0 supraglottic laryngeal squamous cell carcinoma.