Journal of China Pharmaceutical University 2001;(3):221-223
Antagonistic Effects of Extracts from Cultural Mycelium of Cordyceps sinensis on Arrhythmia
Xiaojian GONG ; Hui JI ; Qi CAO ; Shaoping LI ; Ping LI
Country
China
Language
Chinese
Abstract
AIM The purpose is to study the anti-arrhythmic effects of extracts from cultured Cordyceps sinensis. METHODS Aconitine and barium chloride were used to induce experimental arrhythmia models in rats. RESULTS The results showed that PE was more potent than other ingredients. Pretreatment with PE by oral administration significantly antagonized arrhythmia induced by aconitine. PE significantly prolonged the onset of arrhythmia, decreased the duration and diminished the degree of severity. And in barium chloride-induced arrhythmia model, PE had some anti-arrhythmia effect，which could diminish the degree of severity effectively to some extent. CONCLUSION PE is an active component to antagonize arrhythmia induced by aconitine and barium chloride.
备案号: 11010502037788, 京ICP备10218182号-8)