2-(3-benzoylphenyl)propionitrile which is an important intermediate of ketoprofen was synthesized through phase-transfer catalytic by four steps, involving Friedel-crafts reaction, bromination and cyanation. Pure compound was obtained, and the content of crystal was about 98%.AIM　The content of 2-(3-benzoylphenyl)propionitrile was improved. METHODS　Phase-transfer catalytic methylation and suitable method of aftertreatment were used. RESULTS　The yield and content was both improved. CONCLUSION　Phase-transfer catalytic methylation was the best method, and suitable method of aftertreatment was essential.