Chinese Pharmaceutical Journal 2001;(3):172-173
Study on the preparation of piroxicam films
Ping ZHOU
Country
China
Language
Chinese
Abstract
OBJECTIVE To prepare the piroxicam films and study its characteristics of transdermal delivery.METHODS Different high polymers were employed to prepare piroxicam films.Rat abdomen skin and modified Franz diffusion cells were used in the drug penetration tests and release tests.The percutaneous penetration rate was investigated.RESULTS The release rate of piroxicam films was 64.31 μg*cm-2*h-1.The in vitro permeation rate was 14.86 μg*cm-2*h-1.The percutaneous penetration rate was 11.94 μg*cm-2*h-1.CONCLUSION Piroxicam films was developed.
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