Chinese Traditional Patent Medicine 2010;(1):75-79

Determination of alkaloid from combination of Rhizoma Coptidis and Fructus Evodiae by TLCS

Fajing LIU ; Dongmei SUN ; Jiahui LU ; Aili XU

Keywords

Rhizoma Coptidis; Fructus Evodiae; TLCS; berberine hydrochloride; palmatine hydrochloride; jatrorrhizine hydrochloride

Country

China

Language

Chinese

Abstract

AIM: To investigate the changes of alkaloid in Rhizorrm Coptidis and Fructus Evodiae before and after combination. METHODS: The content of berberine hydrochloride,palmatine hydrochloride,jatrorrhizine hydrochloride in Rhizoma Coptidis and Fructus Evodiae before and after combination were determined by TLCS.RESULTS : After combination of Rhizoma Coptidis and Fructus Evodiae,contents of berberine hydrochioride,palmatine hydrochloride,jatrorrhizine hydrochloride significantly reduced,among which the reduction of berberine hydrochloride was more obvious.CONCLUSION: In decoction,Fructus Evodiae appears to restrict the alkaloid from Rhizoma Coptidis in order to lower the side effect of Rhizoma Coptidis.