Chinese Journal of Hepatobiliary Surgery 2011;17(10):861-864

doi:10.3760/cma.j.issn.1007-8118.2011.10.026

Research on etiology and pathophysiology of acute-on-chronic liver failure

Guangxiang GU ; Xiaolei SHI ; Yitao DING

Keywords

Acute-on-chronic liver failure; Etiology; Pathophysiology; Progress

Country

China

Language

Chinese

Abstract

Acute-on-chronic liver failure is a common form of liver failure characterized by complicated clinical manifestations and high mortality.The pathophysiology of ACLF is still unclear.More efficacious treatments are based mainly on a better understanding of the pathophysiology of ACLF.The advances in the pathophysiology of ACLF have been extremely encouraging in the last few years.In this article,we reviewed the progress of ACLF,its definition,etiology and,pathophysiology.