Chinese Journal of Hepatobiliary Surgery 2011;17(10):805-808

doi:10.3760/cma.j.issn.1007-8118.2011.10.004

Value of the conventional liver function tests in the assessment of hepatic reserve

Bin LI ; Yao YU ; Yifeng HE ; Jia FAN ; Zhiquan WU ; Jian ZHOU ; Lunxiu QIN ; Qinghai YE ; Huichuan SUN ; Shuangjian QIU

Keywords

Prealbumin; Hepatic reserve; Hepatic decompensation; Liver failure

Country

China

Language

Chinese

Abstract

Objective To study the risk factors of post-hepatectomy hepatic decompensation (PHD) in patients with hepatocellular carcinoma.MethodWe reviewed 562 patients with Child-Pugh A classification,who underwent partial hepatectomy for hepatocellular carcinoma at Zhongshan Hospital,Fudan University between July 1st 2007 to December 31st 2007,to study the risk factors of hepatic decompensation.ResultsPreoperative high total bilirubin (TB) and low prealbumin (PA) were independent risk factors of PHD by logistic multivariate analysis ROC analysis revealed the cut-offs of preoperative PA predicting PHD were 0.14 g/L (sensitivity 41.4％; specificity 83.1％).The incidence of PHD was 16.0％ when TB≥20.4 μmol/L and PA＜0.14 g/L(OR=7.276,P=0.002).ConclusionThe Child-Pugh A patients recovered well when the preoperative liver function was as follows:TB＜20.4 μmol/L and PA≥0.14 g/L.