Virologica Sinica 2011;26(2):73-80

doi:10.1007/s12250-011-3186-9

Laboratory Detection and Diagnosis of Filoviruses

Yunpeng WANG ; Xianen ZHANG ; Hongping WEI

Keywords

Filovirus; Ebola virus(EBOV); Marburg virus(MARV); Enzyme-linked immunosorbent assay(ELISA); Polymerase chain reaction(PCR)

Country

China

Language

Chinese

Abstract

Ebola virus(EBOV)and Marburg virus(MARV),belonging to the Filoviridae family,emerged four decades ago and caused severe viral hemorrhagic fever in human and other primates.As high as 50-90% mortality,filoviruses can cause significant threats to public health.However,so far no specific and efficient vaccine has been available,nor have other treatment methods proved to be effective.It is of great importance to detect these pathogens specific,rapidly and sensitively in order to control future filovirus outbreaks.Here,recent progresses in the development of detection and diagnosis methods for EBOV and MARV are summarized.