Journal of Jilin University(Medicine Edition) 1999;25(3):221-222

Dynamic observation on bone mineral density of unsexed rabbits with QCT

Yong HAN ; Guizhi WANG ; Guang ZHANG ; Jing SUN ; Jingxin LIU

Keywords

osteoporosis; bone mineral density; extrogen

Country

China

Language

Chinese

Abstract

Objective: The purpose of this tudy was to dynamicly observe the weight and the bone mineral density (BMD) of the unsexed rabbits with a few self-made standardized phantoms. Methods:The eighteen healthy adult female rabbits were measured for their weight and BMD in preunsexed and postunsexed 5 months, 10 months with quantitative CT(QCT). Results:There were 61.1% of rabbits whose weight and BMD decreased after 5 months of the postunsexed and 100% of rabbits whose weight and BMD decreased after 10 months of the operation. Conclusion:QCT can be used to dynamicly observe curative effect of drugs in various periods as well,and it is a good method to study osteoporosis.