Since 1959,the Department of Medical Education at the University of Illinois at Chicago(UIC DME)has experienced five stages,i.e.,formation,going to the world,turmoil,consolidation and prosperous prospects.UIC DME has been contributing a lot to its home institute,medical schools in the United States and also the world's health professions education.There are many aspect,;worth learning from it:such as variOtis institution-based services;multi-discipline faculty for the department;innovative multi-field researches;efficient and effective communication and stimulation for faculty and staff;fruitful collaboration with other organizations and winning active leadership supports.