Progress of Anatomical Sciences 2001;7(1):27-29
Immunohistochemical Study of Insulin-Like Growth Factor-I in Human Fetal Organs
Fan WANG ; Huijun YANG ; Ruixiang LI ; Aidong LI
Country
China
Language
Chinese
Abstract
Objective To study the distribution of insulin-like Growth Factors (IGFs) in liver、 spleen、kidney、thymus and supraadrenal glands of fetus from 16 to 24 weeks.Method Using ABC immunohistochemistry. Results IGF-I positive cells were found in these organs during this period of fetal life, but the differences of number and reaction intensity of IGF-I positive cells appeared in different organs and individuals.Conclusion These organs tissues can express IGF-I during fetal development and play paracrine and/or autocrine role in cellular proliferation and differentiation of these fetal tissue.
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