Acta Laboratorium Animalis Scientia Sinica 2009;17(6):460-464

Immunological Characteristics of Beige-Nude Mice:Research and Development

Rong MA ; Minggang BI

Keywords

Immunodeficient Mice; Beige-Nude; Immunologic characteristics

Country

China

Language

Chinese

Abstract

Immunodeficient animals are animal models that are suitable for medical research. Beige-Nude mice are deficient in both T lymphocytes and natual killer (NK) cells simultaneously. The T cell activity and NK cell activity are much lower in Beige-Nude mice. They were bred for cancer research at first. Researchers have studied the immunologic characteristics of Beige-Nude mice vastly and deeply since 1970s. So this expands its application in medical research.