International Journal of Cerebrovascular Diseases 2009;17(11):871-875

doi:10.3760/cma.j.issn.1673-4165.2009.11.011

Thrombolytic strategies for acute ischemic stroke

Meijuan ZHANG ; Yun XU

Keywords

stroke; thrombolytic therapy; embolectomy; ultrasonic therapy

Country

China

Language

Chinese

Abstract

Thrombolytic therapy is a main treatment method for ischemic stroke.Intravenous recombinant tissue-type plasminogen activator (rtPA) is the only FDA-approved therapy for acute stroke; however,its clinical application has been limited because the narrow therapeutic time window and the presence of the risk of hemorrhagic complication.In order solve these problems,a large number of clinical trials have started to focus on the studies of intra-arterial thrombolysis,mechanical thrombolysis and sonothrombolysis.