Journal of International Oncology 2009;36(11):858-861

doi:10.3760/cma.j.jssn.1673-422X.2009.11.020

Histopathological regression after preoperative chemoradiotherapy in locally advanced rectal carcinoma

Shubo DING

Keywords

Rectal neoplasms; Chemotherapy,adjuvant; Radiotherapy,adjuvant; Histopathological regression

Country

China

Language

Chinese

Abstract

Neoadjuvant chemoradiotherapy (CRT) has become a standard treatment of locally advanced rectal carcinomas. There is a close correlation between histopathological regression after preoperative CRT and prognosis. To identify the markers for histopathological regression is significant for clinical treatment. Different strategies of chemoradiotherapy, application of targeted drugs in neoadjuvant chemothercepy and internal from neoodjuvant to operation are correlated with histopathological regression.