International Journal of Surgery 2009;36(12):843-846

doi:10.3760/cma.j.issn.1673-4203.2009.12.020

Function of BMP7 in the genesis and development of colorectal cancer

Zhong REN ; Liqing YAO

Keywords

bone morphogenetic protein 7 (BMPT); transforming growth factor-β; the genesis and de-velopment of cancer

Country

China

Language

Chinese

Abstract

The family of bone morphogenetic proteins (BMPs) belongs to the superfamily of transforming growth factor-β (TGF-β). It has various functions in the body. In recent years the BMPs family(especially the BMP7) has been discovered to play an important role on the genesis and development of cancer. In this article the characteristic, the mechanism and the function of BMP7 in the genesis and development of cancer are summarized.