International Journal of Cerebrovascular Diseases 2010;18(7):532-536

doi:10.3760/cma.j.issn.1673-4165.2010.07.011

Vascular endothelial growth factor and cerebral infarction

Ke DENG ; Xiaoqiu WU ; Zhijie XIAO

Keywords

Vascular endothelial growth factors; Receptors,vascular endothelial growth factor; Brain infarction

Country

China

Language

Chinese

Abstract

Vascular endothelial growth factor is a vascular endothelial cell-specific mitogen.It is the most important angiogenic factor.VEGF expresses highly after cerebral infarction.It plays importmt roles in angiogenesis and neuroprotection.At the same time,its overexpression will also increase vascular permeability;thereby it may aggravate brain edema.This article reviews the advances in research on VEGF and its receptors and cerebral infarction.