More recently, the Pediatric Quality of Life Inventory Measurement Model (PedsQLTM)is wildly applicated in the research of pediatric quality of life as a pediatric population health measure. Considerable emphasis has been placed on the measurement of the quality of life of children with cerebral palsy, and many scholars carried on the investigations using the PedsQLTM abroad, while there was no related literature reported presently in China. This paper summarizes the basic structure and scoring method of PedsQLTM, and synthetically sums up the determinations of reliability, validity, and sensitivity of PedsQLTM in cerebral palsy children, and gives an overview of the effects on assessment of clinical efficacy and making a medical decision. The PedsQLTM has some superiority in measuring the quality of life in cerebral palsy children.