Oxidative stress has been demonstrated to be one of the important mechanisms for brain injury. Free radicals are one of the most important products following cerebral ischemia/reperfusion and intracerebral hemorrhage. They are the important markers for evaluating the 2 types of stroke injuries. At present, some relevant biomarkers of oxidative stress, such as lipid, DNA, protein peroxidation, antioxidant enzymes, and non-enzymatic antioxidant molecules as well as inflammatory and anti-inflammatory factors, are increasingly receiving attention. This article reviews and evaluates the biomarkers of oxidative stress in stroke.