Objective To introduce the development of transportable-like multi-purpose body posture tables and observe its clinical application effect. Methods The transportable-like multi-purpose body posture tables were independently designed and manufactured. 120 patients who were to receive thoracentesis were divided into the observation group (odd number) and the control group (even number), with 60 cases in each group. The control group uses the traditional method, while the observation group used the transportable-like multi-purpose body posture table during thoracentesis. Pulses,breath, the artery blood oxygen saturation degree were compared between two groups, at the same time, patient comfort levels and degree of satisfaction were also compared. Results After puncture pulse, breathing and arterial oxygen saturation increased in both groups,but showing significant difference between the two groups. Comfort and satisfaction degree of patients in the observation group was significantly better than the control group. Conclusions Portable multi-position table can reduce patient discomfort and improve patient tolerance of surgery, comfort and satisfaction degree.