Chinese Journal of General Practitioners 2010;09(10):723-725
doi:10.3760/cma.j.issn.1671-7368.2010.10.023
Concurrent versus sequential adjuvant radio-chemotherapy after mastectomy for breast cancer: a Meta-analysis
Qing MA ; Yali LIU ; Zhongqing ZHENG ; Yaoyao REN ; Kehu YANG ; Li MA
Keywords
Breast neoplasms; Meta-analysis
Country
China
Language
Chinese
Abstract
With computer and manual search of literatures on the comparison of concurrent with sequential adjuvant radio-chemotherapy after mastectomy for breast cancer, 4 eligible randomized controlled trials were found; the RevMan 5.0 software was used for Meta-analysis. The results showed that concurrent radio-chemotherapy reduced local recurrence more prominently than sequential radio-chemotherapy in patients with positive axillary lymph nodes( P = 0. 003 ). However, differences in 5-year overall survival,5-year disease-free survival and metastasis-free survival between two groups were not significant (P =0. 670,P =0. 200, P =0. 350).
备案号: 11010502037788, 京ICP备10218182号-8)