Journal of International Oncology 2010;37(9):668-671

doi:10.3760/cma.j.issn.1673-422X.2010.09.009

Detection and clinic implication of circulating tumor cells in peripheral blood

Gang XU

Keywords

Circulating tumor cells; Neoplasm metastasis; Immunomagneticbeads; Reverse transcriptase polymerase chain reaction

Country

China

Language

Chinese

Abstract

Circulating tumor cells are closely related to the development and progression of malignant tumors. Current methods of detecting circulating tumor cells include reverse transcription polymerase chain reaction method and immunomagnetic enrichment assay. Detection of circulating tumor cells can contribute to early detection of cancer micrometastases, re-classification of clinical stage, monitoring recurrence and metastasis after surgery or radiotherapy and chemotherapy, predicting prognosis, and selecting personalized therapeutic strategy.