Chinese Journal of Clinical Nutrition 2010;18(2):121-123

doi:10.3760/cma.j.issn.1674-635X.2010.02.013

Effectiveness of aspirin in preventing peripherally inserted central venous catheter-related thrombosis

Xuying LI ; Zhenqiu SUN ; Yongyi CHEN ; Jinhua LI ; Zhong YUAN ; Yuhua WANG

Keywords

Aspirin; Peripherally inserted central venous catheter; Thrombosis; Phlebitis

Country

China

Language

Chinese

Abstract

Objective To evaluate the effectiveness of aspirin in preventing peripherally inserted central venous catheter (PICC) -related thrombosis. Methods Totally 360 cancer patients who had undergone routine PICC placement were equally randomized into aspirin group (receiving conventional PICC maintenance plus oral administration of aspirin; 100 mg/d, for consecutively 21 days) and control group (conventional PICC catheter maintenance). The incidences of phlebitis and thrombosis were observed in both two groups. Results The incidences of phlebitis and thrombosis were 3.3% and 0 in aspirin group, which were significantly lower than those in control group (8.9% , P = 0. 025; 1.7% , P = 0. 025). Conclusion The oral administration of aspirin after the PICC placement can reduce PICC-related thrombosis and phlebitis.