Chinese Journal of Clinical Infectious Diseases 2010;03(5):290-294

doi:10.3760/cma.j.issn.1674-2397.2010.05.011

Efflux pumps in multidrug resistant Escherichia coli

Weihua WANG ; Li WANG ; Wanfei Lü ; Jie CHEN ; Yuanyuan ZHANG ; Xiongying MAO ; Hui CHEN

Keywords

Escherichia coli; Efflux pumps; Multidrug resistant; Gene

Country

China

Language

Chinese

Abstract

Objective To explore the prevalence of 11 efflux pumps in isolates of multidrugresistant Escherichia coli(MDR-ECO). Methods Efflux pumps emrB, emrD , emrE, mdfA, sugE, mdtl,tehA, oqxA, qacE△1, qacE and smr-2 were detected by polymerase chain reaction(PCR)in 20 MDR-ECOs isolated from clinical samples. Results Efflux pumps emrB, emrD, emrE, mdfA, sugE, mdtI, qacE △1, tehA and oqxA were detected, and 8 efflux pumps were found in the same strain. Conclusion Multidrug- resistance in Escherichia coli may be related with efflux pumps.