International Journal of Cerebrovascular Diseases 2010;18(11):860-864

doi:10.3760/cma.j.issn.1673-4165.2010.11.013

Induced pluripotent stem cells and their application in research and treatment of cerebrovascular disease

Wei LIAO ; Yang WANG ; Zhifeng DENG

Keywords

Pluripotent stem cells; Nuclear reprogramming; Cell differentiation; Neurons; Cerebrovascular disorders; Cell transplantation

Country

China

Language

Chinese

Abstract

Induced pluripotent stem (iPS) cells are reprogrammed by the differentiated adult cells, ard in terms of biological characteristics they are remarkably similar to embryonic stem cells. Compared to the embryonic stem cells, the iPS cells are unrestricted by cell resources, immune rejection and ethics, They maintain the advantages such as specific individual genes, and provide potential cell resources for the fields of regenerative medicine and tissue engineering, This article mainly introduces the iPS cells and their application in the research and treatment of cerebrovascular diseases.