This paper aimed at evaluating clinical value of multi-slice spiral computed tomography (MSCT) with post-processing technology in diagnosis for lamina papyracea fracture (LPF). Volume scanning with MSCT was performed for 97 cases with LPF followed by post-processing with axial highresolution reconstruction, coronal multi-planar reformation ( CMPR), coronal maximum intensity projection (CMIP) and volume rendering (VR). Obtained images in the patients with fracture were compared with their primary axial scanning, including 42 with line-type fracture without obvious dislocation, 48 cases with depression fracture with dislocation, and seven cases with non-depression fracture showing dislocation.Twelve of them displayed "two margins sign", seven diagnosed by CMPR and CMIP images and five by VR combined with CMPR. Thirty-nine cases complicated with swelling of the intraocular muscle, 25 with intraorbital fat hernia into the ethmoid sinus, 66 cases with intraorbital air and liquid deposited at the ethmoid sinus, and 15 with retro-bulbar hemorrhage. MSCT with post-processing technology can accurately display direct and indirect signs of LPF which can be further divided into varied types, and is the most effective method in clinical diagnosis.