Journal of International Oncology 2011;38(1):60-63

doi:10.3760/cma.j.issn.1673-422X.2011.01.020

DNA double-strand break repair and ovarian cancer

Weizhi YOU ; Shiqian ZHANG ; Ling ZHANG

Keywords

Ovarian neoplasms; DNA repair

Country

China

Language

Chinese

Abstract

DNA double-strand break repair (DSBR) pathways are important repair pathways in human. DSBR pathways repair damaged DNA, maintain the integrity of the genetic information and therefore suppress cancer. More and more researches have indicated important roles of DSBR pathway genes in the development and treatment of ovarian cancer.