Virologica Sinica 2011;26(1):1-7

doi:10.1007/s12250-011-3159-4

Advances of Bioinformatics Tools Applied in Virus Epitopes Prediction

Ping CHEN ; Simon RAYNER ; Kanghong HU

Keywords

Epitope; Bioinformatics; Epitope prediction algorithms

Country

China

Language

Chinese

Abstract

In recent years, the in silico epitopes prediction tools have facilitated the progress of vaccines development significantly and many have been applied to predict epitopes in viruses successfully. Herein, a general overview of different tools currently available, including T cell and B cell epitopes prediction tools, is presented. And the principles of different prediction algorithms are reviewed briefly. Finally, several examples are present to illustrate the application of the prediction tools.