Chinese Journal of Ocular Fundus Diseases 2009;25(4):247-248

doi:10.3760/cma.j.issn.1005-1015.2009.04.01

Somatic reprogramming:new breakthrough in researches on stem cells

Jian GE

Keywords

Stem cells/cytology; Stem cells/classification; Stem cell transplantation; Retinal diseases/diagnosis; Animals,laboratory

Country

China

Language

Chinese

Abstract

Replacement therapy of stem cells transplantation represents a potential treatment for neural retinal diseases.Despite the encouraging results in laboratory,the clinical application of cells replacement therapy is still difficult because the limitation of seed cells,immunologic rejection,oncogenicity and ethical problems,etc.Recent breakthrough in somatic reprogramming provides a promising solution overcoming these obstacles.Further researches on virus-free reprogramming will make the clinical application of stem cell replacement therapy possible.