Chinese Journal of Laboratory Medicine 2009;32(9):1064-1068

doi:10.3760/cma.j.issn.1009-9158.2009.09.025

A novel base-quenched probe technique for detecting single-nucleotide polymorphisms

Jun ZHANG ; Guanghua LUO ; Lu ZHENG ; Xiaoying ZHANG ; Ning XU

Keywords

Polymorphism; single nucleotide; Genotype; Nucleic acid probes

Country

China

Language

Chinese

Abstract

ncing analysis validated that all four-type base-quenched probes could provide unbiased genotyping results ( Kappa =1, P=0.00), although. Conclusion This method is simple, economic and suitable for large-scale genotyping studies.