Dementia and Neurocognitive Disorders  2015;14(1):48-51

doi:10.12779/dnd.2015.14.1.48

Reversible Amygdala and Parahippocampal Lesions of Brain 18Fluorodeoxy Glucose-Positron Emission Tomography in Neuropsychiatric Systemic Lupus Erythematosus.

Do Young YOON 1 ; Doo Yong PARK ; Subin LEE ; Jee Young KIM ; Hyun Jeong HAN ; Eun Jung KIM

Affiliations

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Keywords

systemic lupus erythematosus; neuropsychiatric manifestations; brain 18fluorodeoxy glucose-positron emission tomography

Country

Republic of Korea

Language

English

Abstract

BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune disease that is a significant source of morbidity and mortality when it manifests in the central nervous system. The early detection and treatment of neuropsychiatric SLE (NPSLE) is very important, but a confirmative diagnostic tool has yet to be developed. CASE REPORT: We report here a case of neuropsychiatric manifestations in a patient that were associated with SLE, and evidence of reversal of bilateral amygdala and parahippocampal lesions in the brain revealed by 18fluorodeoxy glucose-positron emission tomography. CONCLUSIONS: We are suggestive of 18fluorodeoxy glucose-positron emission tomography appear to be more sensitive in detecting subtle brain changes in NPSLE.