PURPOSE: The purpose of this study was to identify the effects of social support on the relationship between practice stress, emotional labor, and burnout among nursing students. METHODS: The sample for this study consisted of 199 students from four universities located in Korea, and had a practicum experience at least one semester before the study began. Data were analyzed using descriptive statistics, t-test, ANOVA, Scheffé test, Pearson correlation and hierarchical multiple regression with SPSS/WIN 23.0. RESULTS: It was found that: (a) burnout had a positive correlation with both practice stress and emotional labor, whereas a negative correlation was observed with social support; (b) social support mediated the relationship between practice stress and burnout, and (c) social support mediated the relationship between emotional labor and burnout. CONCLUSION: Results of the study suggest that social support decreases the negative effects of practice stress and emotional labor on burnout. Therefore, we need to find ways to strengthen social support for students.