Journal of Asthma, Allergy and Clinical Immunology  1998;18(3):504-509

A case of drug - induced linear IgA bullous dermatosis.

Sang Hee HAM ; Seog Jun HA ; Young Min PARK ; Sang Hyun CHO ; Jin Wou KIM ; Baik Kee CHO

Keywords

Linear IgA bullous dermatosis; drug

Country

Republic of Korea

Language

Korean

Abstract

Linear IgA bullous dermatosis (LABD) is an autoimmune subepidermal blistering disease characterized on direct immunofluorescence of perilesional skin by the linear deposition of IgA at the basement membrane zone. The pathogenesis of LABD is not known, but rar ely some cases of LABD have been reported in association with drug exposure. We report a case of drug-induced LABD showing linear deposits of IgA and IgG at the basement membrane zone on direct immunofluorescence of perilesional skin as well as typical clinical and histologic characteristics, although the causative agent could not be specified.