Pediatric Gastroenterology, Hepatology & Nutrition  2013;16(1):22-27

doi:10.5223/pghn.2013.16.1.22

Gut Microbiota and Clinical Disease: Obesity and Nonalcoholic Fatty Liver Disease.

Ji Sook PARK 1 ; Ji Hyun SEO ; Hee Shang YOUN

Affiliations

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Keywords

Obesity; Microbiota; Non-alcoholic fatty liver disease

Country

Republic of Korea

Language

English

Abstract

The prevalence of obesity is increasing worldwide. Obesity can cause hyperlipidemia, hypertension, cardiovascular diseases, metabolic syndrome and non-alcoholic fatty liver disease (NAFLD). Many environmental or genetic factors have been suggested to contribute to the development of obesity, but there is no satisfactory explanation for its increased prevalence. This review discusses the latest updates on the role of the gut microbiota in obesity and NAFLD.