Chinese Journal of Gastrointestinal Surgery 2006;9(2):107-110

Changes of sphincter preserving rate in lower rectal cancer and analysis of their related factors.

Jian-ping WANG 1 ; Xiao-jian WU ; Xin-ming SONG ; Lei WANG ; Mei-jin HUANG ; Ping LAN

Affiliations

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Country

China

Language

Chinese

Abstract

OBJECTIVETo analyze the factors related to sphincter preserving(SP) operation for lower rectal cancer.

METHODSClinicopathological data of 316 patients with lower rectal cancer 1-5 cm from the anorectal line who underwent surgical resection from Aug. 1994 to Nov. 2005 were analyzed. The whole period was divided into two period based on the introduction of TME in Jan. 1999. The SP rates, leakage between the two period were compared.

RESULTSThe SP rate increased significantly from 44.9 % in period I (Aug. 1994-Dec. 1998) to 76.2 % in period II (Jan. 1999-Nov. 2005)(P=0.000). The factors significantly influencing SP were the distance from the anorectal line, sex, period, circumference of intramural spread, histological differentiation (P< 0.05). Significant differences were detected between the two period in sex, volume of blood transfusion, Dukes' stage (P< 0.05). The rate of leakage were 2.7 % and 1.3 % in the two period (P > 0.05).

CONCLUSIONSOver 12 years, the SP rate of rectal cancers 1-5 cm from the anorectal line was significantly increased and volume of blood transfusion reduced obviously due to the introduction of TME. These surgical techniques, however, have no effect on the operating time and leakage rates.