Obstetrics & Gynecology Science  2017;60(1):118-123

doi:10.5468/ogs.2017.60.1.118

Lymphoepithelioma-like carcinoma of the uterine cervix.

Hyun Sil YUN 1 ; Sun Kyung LEE ; Gun YOON ; Hwi Gon KIM ; Dong Hyung LEE ; Yong Jin NA ; Ook Hwan CHOI ; Dong Hoon SHIN ; Yong Jung SONG

Affiliations

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Keywords

Cervix uteri; Herpesvirus 4, human; Lymphoepithelioma-like carcinoma; Uterine cervical neoplasms

Country

Republic of Korea

Language

English

Abstract

Lymphoepithelioma-like carcinoma (LELC) of the uterine cervix is exceedingly uncommon. We herein report a rare case of cervical LELC. A 45-year-old woman was admitted to gynecology department with vaginal bleeding for one month. Liquid-based cytology revealed atypical endometrial cells, not otherwise specified on her cervix. On a hysteroscopy, an endocervical mass was identified and the pathologic result was consistent with poorly differentiated squamous cell carcinoma. Magnetic resonance imaging and positron emission tomography with 2-deoxy-2-[fluorine-18] fluoro-D-glucose integrated with computed tomography revealed a 3.1-cm endocervical mass without distant metastasis or enlarged lymph nodes. The International Federation of Gynecology and Obstetrics stage was IB1. A radical hysterectomy and bilateral pelvic lymph node dissection were performed. The pathologic diagnosis was a poorly differentiated carcinoma, showing features of LELC. She has been followed for 8 months without adjuvant treatment since the surgery, during which time there has been no evidence of tumor recurrence or metastasis.