Obstetrics & Gynecology Science  2017;60(1):124-128

doi:10.5468/ogs.2017.60.1.124

Extrauterine epithelioid trophoblastic tumor in hysterectomized woman.

Ji Hye KIM 1 ; Sun Kyung LEE ; Soo Hyun HWANG ; Jung Sun KIM ; Gun YOON ; Yoo Young LEE ; Tae Joong KIM ; Chel Hun CHOI ; Byoung Gie KIM ; Duk Soo BAE ; Jeong Won LEE

Affiliations

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Keywords

Beta human chorionic gonadotropin; Epithelioid trophoblastic tumor; Gestational trophoblastic disease

Country

Republic of Korea

Language

English

Abstract

Epithelioid trophoblastic tumor (ETT) is a very rare variant of gestational trophoblastic disease (GTD) which arises in reproductive age women with prior gestational history. Although abnormal vaginal bleeding is the most common symptom of ETT, there are no reported pathognomonic symptoms of ETT because of its rarity. ETT is similar to placental site trophoblastic tumor in terms of its slow growing characteristic and microscopic findings. Therefore, it could be misdiagnosed as placental site trophoblastic tumor or other types of GTD. Unlike other types of GTD, primary treatment of ETT is surgical resection because of its chemo-resistant nature. Accordingly, immunohistochemical staining is essential for accurate diagnosis and appropriate treatment. Here, we report a case of a 42-year-old hysterectomized woman with pelvic masses who suffered from abdominal pain. Through laparotomy, tumors were resected completely and they were diagnosed as ETT through immunohistochemical stain. This report provides more evidence about its clinical features, diagnosis, and treatment including a brief review of the literature.