Obstetrics & Gynecology Science  2017;60(1):133-137

doi:10.5468/ogs.2017.60.1.133

Pregnancy-related osteoporosis and spinal fractures.

Ka Yeong YUN 1 ; Si Eun HAN ; Seung Chul KIM ; Jong Kil JOO ; Kyu Sup LEE

Affiliations

+expand

Keywords

Fractures; compression; Osteoporosis; Pregnancy

Country

Republic of Korea

Language

English

Abstract

Pregnancy-related osteoporosis is a very rare condition characterized by the occurrence of fracture during pregnancy or the puerperium. Despite its relative rarity, it can be a dangerous condition that causes severe back pain, height loss and disability. Normal physiologic changes during pregnancy, genetic or racial difference, obstetrical history and obstetrical disease, such as preterm labor or pregnancy-induced hypertension, are presumed risk factors of pregnancy-related osteooporosis. However, exact etiology and pathogenesis are uncertain. The management and natural history are still poorly defined. Traditional medications for osteoporosis are calcium/vitamin D and bisphosphonate. Concerns with bisphosphonate include accumulation in bone and fetal exposure in subsequent pregnancies. The newly developed medication, teriparatide, has shown good results. We report six cases of pregnancy-related osteoporosis and spinal fracture with literature review.