Journal of Biomedical Engineering 2003;20(1):14-16

Study on the cytocompatibility of biodegradable poly(epsilon-caprolactone) microspheres in vitro.

Qizhi LUO 1 ; Jianhai CHEN ; Kaijin DAI

Affiliations

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Country

China

Language

Chinese

Abstract

Poly(epsilon-caprolactone) microspheres were fabricated with an average particle size of 5.08 +/- 0.23 microns. The effect of poly(epsilon-caprolactone) microspheres on apoptosis and cell cycle of fibroblast was studied with flow cytometry. The data obtained clearly indicated that poly(epsilon-caprolactone) microspheres purified in different ways showed different cytocompatibility. The well purified microspheres have good cytocompatibility.