Nuclear Medicine and Molecular Imaging  2009;43(4):361-362

A Neurofibroma Confused with Sarcomatous Transformation on F-18 FDG PET/CT in Neurofibromatosis-1.

Soon Ah PARK 1 ; Jeong Hoon SONG ; Chung Yong YANG ; Hun Soo KIM ; Seung Chol PARK

Affiliations

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Keywords

PET/CT; F-18 fluorodeoxyglucose; neurofibromatosis

Country

Republic of Korea

Language

English

Abstract

We present a patient with high 18F-fluorodeoxyglucose (FDG) uptake detected in a neurofibroma that was confused with sarcomatous transformation on a positron emission tomography/computed tomography (PET/CT) scan. A 39-year-old male patient with a 20-year history of neurofibromatosis-1 (NF-1) performed FDG PET/CT scan for the evaluation of lesions with sarcomatous transformation. The FDG PET/CT images demonstrated varying degrees of increased FDG uptake in the multiple nodules throughout whole body. The left pelvic mass with the highest FDG uptake had a maximum standardized uptake values (maxSUV) 5.0 and surgical resection was performed. Histological analysis confirmed the presence of a benign neurofibroma infiltrated with inflammatory cells.