Experimental Neurobiology  2017;26(1):66-69

doi:10.5607/en.2017.26.1.66

Relapsing Polychondritis Presented with Encephalitis Followed by Brain Atrophy.

Suk Won AHN 1 ; Moo Seok PARK ; Hae Bong JEONG ; Oh Sang KWON ; Byung Nam YOON ; Hee Sung KIM ; Sang Tae CHOI

Affiliations

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Keywords

Relapsing polychondritis; Encephalitis; Brain atrophy; Multiple sclerosis; Neuromyelitis optica

Country

Republic of Korea

Language

English

Abstract

Relapsing polychondritis (RP) is a rare autoimmune disease that is characterized by inflammatory reaction of unknown etiology and destruction of cartilaginous structures. Characteristic symptoms of this disease include cartilage inflammation of the ear, nose, larynx, trachea, bronchi, joints, eyes, heart and skin. Concomitance with neurologic symptom is very rare in RP, and the detailed underlying mechanism of neurological involvement associated with RP is not fully understood. We herein described an unusual recurrent case of inflammatory brain lesions associated with RP, with attention to clinical manifestations, autoimmune disease involvement, and therapeutic effects.