Korean Journal of Pancreas and Biliary Tract  2015;20(3):136-139

doi:10.15279/kpba.2015.20.3.136

A Case of Acute Pancreatitis Caused by Bortezomib in a Patient with Multiple Myeloma.

Jae Hong LIM 1 ; Kyo Bum HWANG ; Byung Hun LIM ; Young Hoon JEONG ; Ki Chang SOHN ; Tae Hyeon KIM

Affiliations

+expand

Keywords

Pancreatitis; Multiple myeloma; Bortezomib

Country

Republic of Korea

Language

Korean

Abstract

Bortezomib is a proteasome inhibitor used for the treatment of patients with multiple myeloma. Recently, several case reports about acute pancreatitis caused by Bortezomib were published in the international literature. But Bortezomib induced pancreatitis case was not reported in Korea. Herein, we report a case of acute pancreatitis caused by Bortezomib therapy in a 76-year-old female with multiple myeloma. On three months after the first administration of Bortezomib, the patient visited the hospital with symptoms of acute pancreatitis. The common etiological factors for acute pancreatitis were all excluded. Then the patient was diagnosed as Bortezomib-induced pancreatitis. After cessation of Bortezomib, she showed clinical and laboratory improvement.