China Journal of Orthopaedics and Traumatology 2010;23(4):320-323

Wnt signaling pathways and osteoarthritis.

Ning-Yang GAO 1 2 ; Yue-Long CAO ; Ting LIU ; Jian PANG ; Hong-Sheng ZHAN ; Yin-Yu SHI

Affiliations

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Country

China

Language

Chinese

Abstract

The Wnt signaling exists in every kinds of species and regulates a variety of biological processes including cell fate, proliferation and function, immunity, stress, apoptosis and so on. During the researching, Wnt signaling also plays an important role in chondrocyte differentiation and maturation. So it has been the new spot in pathogenesis of osteoarthritis study.