Pediatric Gastroenterology, Hepatology & Nutrition  2017;20(2):124-129

doi:10.5223/pghn.2017.20.2.124

Pediatric Mycoplasma pneumoniae Infection Presenting with Acute Cholestatic Hepatitis and Other Extrapulmonary Manifestations in the Absence of Pneumonia.

Won Jae SONG 1 ; Ben KANG ; Hwa Pyung LEE ; Joongbum CHO ; Hae Jeong LEE ; Yon Ho CHOE

Affiliations

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Keywords

Hepatitis; Mycoplasma pneumoniae; Extrapulmonary manifestation

Country

Republic of Korea

Language

English

Abstract

Mycoplasma pneumoniae infections mainly involve respiratory tract; however, also can manifestate other symptoms by site involved. Extrapulmonary manifestations of M. pneumoniae infection are rarely known to occur without pneumonia. Herein we report a case of a 9-year-old boy who presented with acute cholestatic hepatitis in the absence of pneumonia. Rhabdomyolysis, skin rash, and initial laboratory results suspicious of disseminated intravascular coagulopathy were also observed in this patient. M. pneumoniae infection was identified by a 4-fold increase in immunoglobulin G antibodies to M. pneumoniae between acute and convalescent sera by enzyme-linked immunosorbent assay. This is the first pediatric case in Korea of M. pneumoniae infection presenting with acute cholestatic hepatitis in the absence of pneumonia.