Chinese Journal of Stomatology 2003;38(6):432-434

A study of calcitonin gene-related peptide-immunoreactive nerve fibers of rat molar pulp during traumatic occlusion and after removal.

Zuo-qi HAO 1 ; Hong-chen LIU ; Mei-ling ZHU ; Li-jun DUAN

Affiliations

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Country

China

Language

Chinese

Abstract

OBJECTIVETo study the effect of traumatic occlusion on CGRP-immunoreactive (CGRP-IR) nerve fibres in rat molar pulp and observe the recovery of CGRP-IR nerve fibres after removal of traumatic occlusion.

METHODSTo observe immunohistochemically the change of CGRP-IR nerve fibres in molar pulp during traumatic occlusion and after removal.

RESULTSThe increase of number, density and morphology of CGRP-IR nerve fibres in traumatic occlusion group was more than in control group, however, the changes of CGRP-IR nerve fibres in removal of traumatic occlusion group were less than in control group.

CONCLUSIONSThe changes of CGRP-IR nerve fibres in number, morphology, and density are induced by traumatic occlusion in rat molar pulp, however, the nerve fibres recover to normal by removal of traumatic occlusion.