Journal of Zhejiang University. Medical sciences 2014;43(6):664-669

Risk factors of biliary complications after liver transplantation from donation after cardiac death.

Jun YU 1 ; Shang-Fen XIE 2 ; Wei-Liang XIA 2 ; Long-Yu CHENG 2 ; Wu ZHANG 2 ; Song-Feng YU 2 ; Min ZHANG 2 ; Shu-Sen ZHENG 2 ;

Affiliations

+expand

Country

China

Language

Chinese

Abstract

OBJECTIVETo analyze the risk factors for biliary complications of liver transplantation from donation after cardiac death (DCD).

METHODSClinical data of 109 patients undergoing liver transplantation from DCD in First Affiliated Hospital of Zhejiang University School of Medicine from October 2010 to October 2013 were studied retrospectively. The risk factors of biliary complications following DCD liver transplantation were analyzed.

RESULTSTwenty-four (22%) patients developed biliary complications after DCD liver transplantation. Univariate analysis showed that biliary complications were associated with warm ischemia time (P<0.001) and length of ICU stay (P=0.013), but not associated with ABO blood types match (P>0.05). Administration of inotropic agents and fatty liver increased the trend of biliary complications. Multivariate analysis demonstrated that warm ischemia time and length of ICU stay were independent risk factors for predicting biliary complications.

CONCLUSIONWarm ischemia time and days of ICU stay are independent risk factors for predicting biliary complications after DCD liver transplantation.