Keimyung Medical Journal  2014;33(2):126-131

A Case of Polyostotic Fibrous Dysplasia Masquerading as a Mulptile Bone Metastases.

Jaekyung CHEON 1 ; Yumun JEONG ; Ji Young YANG ; Sunpyo LEE ; Misun CHUNG ; Eun Mi SON ; Jae Lyun LEE

Affiliations

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Keywords

Bone neoplasm; Fibrous dysplasia; Metastasis

Country

Republic of Korea

Language

English

Abstract

Fibrous dysplasia is a benign, bony abnormality that is usually asymptomatic. A 41-year-old male with minimal symptoms presented at this hospital with abnormal findings incidentally seen in his ribs on the chest radiograph. A skeletal survey showed numerous, osteolytic lesions throughout multiple bones. Diagnostic processes for malignancy of undefined primary origin (MUO) were performed in order to identify the underlying primary neoplasm, although abnormal findings were not seen except for multiple bone lesions. A computed tomography guided bone biopsy was performed on his left rib. The final diagnosis was fibrous dysplasia. This case demonstrates that fibrous dysplasia should be considered in the differential diagnosis in young patients with multiple, osteolytic lesions and without a prior history suggesting malignancy.