Brain Tumor Research and Treatment  2014;2(2):124-127

doi:10.14791/btrt.2014.2.2.124

Extraneural Metastases of Glioblastoma without Simultaneous Central Nervous System Recurrence.

Wonki KIM 1 ; Heon YOO ; Sang Hoon SHIN ; Ho Shin GWAK ; Seung Hoon LEE

Affiliations

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Keywords

Glioblastoma multiforme; Neoplasm metastasis; Spinal neoplasms; Pleural effusion; Malignant

Country

Republic of Korea

Language

English

Abstract

Glioblastoma multiforme (GBM) is well known as the most common malignant primary brain tumor. It could easily spread into the adjacent or distant brain tissue by infiltration, direct extension and cerebro-spinal fluid dissemination. The extranueural metastatic spread of GBM is relatively rare but it could have more progressive disease course. We report a 39-year-old man who had multiple bone metastases and malignant pleural effusion of the GBM without primary site recurrence.